Elevated Glucose Impairs the Endothelial Cell Response to Shear Stress
β Scribed by Jeremy B. Brower; Jerome H. Targovnik; Benjamin P. Bowen; Michael R. Caplan; Stephen P. Massia
- Book ID
- 107620689
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 563 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1865-5025
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π SIMILAR VOLUMES
## Abstract Most acute coronary events occur in the upstream region of stenotic atherosclerotic plaques that experience laminar shear stress (LSS) elevated above normal physiological levels. Many studies have described the atheroprotective effect on endothelial behavior of normal physiological LSS
## Abstract An important physiological function of vascular endothelial cells is to detect and respond to physical stimuli. While many efforts have been made to derive endothelial cells from human embryonic stem cells (hESCs), the ability of these derivatives to respond to mechanical forces has yet