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Elevated expression of β1 and β2 integrins, intercellular adhesion molecule 1, and endothelial leukocyte adhesion molecule 1 in the skin of patients with systemic sclerosis of recent onset

✍ Scribed by Stephan Sollberg; Juha Peltonen; Jouni Uitto; Sergio A. Jimenez


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
939 KB
Volume
35
Category
Article
ISSN
0004-3591

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## Objective: To investigate the role of intercellular adhesion molecule 1 (icam-1) and beta2 integrins in the production of superoxide (o2-) by c1q-stimulated human polymorphonuclear leukocytes (pmn). ## Methods: Pmn were pretreated with f(ab')2 fragments of monoclonal antibodies (mab) that bloc