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Elevated C-peptide and insulin predict increased risk of colorectal adenomas in normal mucosa

✍ Scribed by Adriana C Vidal, Pauline Kay Lund, Cathrine Hoyo, Joseph Galanko, Lauren Burcal, Rachel Holston, Berri Massa, Oluwaseun Omofoye, Robert S Sandler, Temitope O Keku

Book ID: 119897434
Publisher: BioMed Central
Year: 2012
Tongue: English
Weight: 206 KB
Volume: 12
Category: Article
ISSN: 1471-2407
DOI: 10.1186/1471-2407-12-389

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## Abstract The physical inactivity and obesity involved in hyperglycemia and hyperinsulinemia is supposed to lead to an increased bioavailability of insulin‐like growth factor‐I (IGF‐I). The carcinogenic effect of IGF‐I may be influenced by IGF binding proteins. We investigated the association bet