Elevated Bcl-2 is not a causal event in the positive selection of T cells
β Scribed by Owen Williams; Chen-Lang Mok; Trisha Norton; Nicola Harker; Dimitris Kioussis; Hugh J. M. Brady
- Book ID
- 101386211
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 121 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0014-2980
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Immune escape driven by selection pressure from virus-specific CD8 T cells has been demonstrated in both chimpanzees and humans infected with the hepatitis C virus (HCV). Although escape mutations have also been characterized in major histocompatibility complex (MHC) class II-restricted HCV epitopes