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Elemental Distribution in the Human Respiratory System and Excretion Organs: Absorption and Accumulation

✍ Scribed by T. Pinheiro; A. Bugalho de Almeida; J. R. Vieira; A. Fernandes; L. C. Alves; M. Reis; J. Carvalho Soares

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 225 KB
Volume: 26
Category: Article
ISSN: 0049-8246
DOI: 10.1002/(sici)1097-4539(199707)26:4<217::aid-xrs215>3.0.co;2-w

No coin nor oath required. For personal study only.

✦ Synopsis

In order to initiate a reference data base for the respiratory system and to understand the e †ects of airborne substances on human health, di †erent sites of the respiratory ducts and respiratory tissue were analysed. Excretion organs related to the removal of inhaled constituents were also assessed in order to infer excretion rates of the chemical species found in the respiratory system. PIXE was applied to the determination of minor and trace elemental contents of trachea, bronchi, lung, liver and kidney samples. Two groups of elements were established : the constitutive elements, known to be essential to cellular metabolism (K, Ca, Mn, Fe, Cu, Zn, Se, Rb and Sr), and the accumulated elements of exogenous origin (Ti, V, Cr, Ni, Zr and Pb). The di †erent patterns of elemental accumulation at excretion organs and in the respiratory system suggest di †erences in the aerodynamic properties and in the chemical affinities or reactivity of inhaled particulate matter with cells.

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