Electrosynthesis of β-methylpentadecanedioic acid dimethyl ester

✍ Scribed by Zhang Zhongcheng; Liu Jiali; Shang Yuxia

• Book ID: 102313799
• Publisher: Wiley (John Wiley & Sons)
• Year: 1995
• Tongue: English
• Weight: 272 KB
• Volume: 64
• Category: Article
• ISSN: 0268-2575
• DOI: 10.1002/jctb.280640304

✦ Synopsis

Methylpentadecanedioic acid dimethyl ester (I) was synthesized electrochemically by Kolbe reaction using P-methylglutaric acid monomethyl ester (11) and a,w-dodecanedioic acid monomethyl ester (111) as starting materials in MeOH solution. Electrolysis was carried out for about 4-5 h, when solution pH 2 7, followed by extraction with petroleum ether and distillation to obtain a colourless oily product (I). The minimum production cost occurred when the mole ratio of I1 to I11 was 1 : 1.38 and unreacted 111 could be recovered. The product synthesized (I) completely met the requirement of artificially synthesized musk.