𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Electrostatic Steering and Ionic Tethering in the Formation of Thrombin−Hirudin Complexes: The Role of the Thrombin Anion-Binding Exosite-I †

✍ Scribed by Myles, Timothy; Le Bonniec, Bernard F.; Betz, Andreas; Stone, Stuart R.

Book ID
126809228
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
97 KB
Volume
40
Category
Article
ISSN
0006-2960

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The fibrinogen anion-binding exosite of
The fibrinogen anion-binding exosite of thrombin is necessary for induction of rises in intracellular calcium and prostacyclin production in endothelial cells
✍ Justinian R. Ngaiza; Geoffrey Manley; Jürgen Grulich-Henn; John L. Krstenansky; 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 719 KB

Thrombin stimulation of prostacyclin (PGI,) synthesis by cultured human umbilical vein endothelial cells (HUVEC) requires the active site of thrombin and involves rapid and transient rises in cytoplasmic free calcium [CaL+],. In this study, we investigated whether or not the anion-binding exosite fo

The Role of Binding Constants in the Eff
The Role of Binding Constants in the Efficiency of Chiral Catalysts Immobilized by Electrostatic Interactions: The Case of Azabis(oxazoline)–Copper Complexes
✍ José M. Fraile; José I. García; Clara I. Herrerías; José A. Mayoral; Oliver Reis 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 175 KB

## Abstract As shown by theoretical calculations, azabis(oxazoline)–copper complexes are considerably more stable than the analogous bis(oxazoline)–copper complexes. This enhanced stability allows them to be efficiently immobilized by means of electrostatic interactions to different anionic support