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Electrostatic Origin of the Catalytic Power of Enzymes and the Role of Preorganized Active Sites

โœ Scribed by Warshel, A.


Book ID
124082875
Publisher
The American Society for Biochemistry and Molecular Biology
Year
1998
Tongue
English
Weight
681 KB
Volume
273
Category
Article
ISSN
0021-9258

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Protein X-ray crystallography has revealed the structures of the active sites of several molybdenum- and tungsten-containing enzymes that catalyze formal hydroxylation and oxygen atom transfer reactions. Each molybdenum (or tungsten) atom is coordinated by one (or two) ene-dithiolate groups of a nov