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Electrostatic interactions in aromatic oligopeptides contribute to protein stability

✍ Scribed by Stephen K. Burley; Gregory A. Petsko


Book ID
113271443
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
753 KB
Volume
7
Category
Article
ISSN
0167-7799

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The challenge of evaluating absolute binding free energies of proteinprotein complexes is addressed using the scaled Protein Dipoles Langevin Dipoles (PDLD/S) model in combination with the Linear Response Approximation (LRA). This is done by taking the complex between Rap1A (Rap) and the p21 ras bin