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Electrostatic interactions between α-helix dipoles in crystals of an uncharged helical undecapeptide

✍ Scribed by Wim G. J. Hol; Marc C. H. De Maeyer

Publisher: Wiley (John Wiley & Sons)
Year: 1984
Tongue: English
Weight: 421 KB
Volume: 23
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.360230418

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✦ Synopsis

The electrostatic interactions between a-helix dipoles in the crystals of an uncharged helical undecapeptide have been studied in detail. The electrostatic interaction energy between one helix dipole and its 26 nearest neighbors is approximately -23 kcal mol-'. A very similar result is obtained when calculating the interactions between one helix dipole and all 988 helix dipoles occurring within a distance of 75 A. It therefore appears that in these crystals of completely uncharged molecules large, favorable electrostatic interactions occur.

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