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Electrostatic Interactions between Peptides and the Molecular Chaperone DnaK

✍ Scribed by Liu, W.; Bratko, D.; Prausnitz, J. M.; Blanch, H. W.


Book ID
125953106
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
85 KB
Volume
107
Category
Article
ISSN
0022-3654

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We describe a methodology to calculate the relative free energies of protein-peptide complex formation. The interaction energy was decomposed into nonpolar, electrostatic and entropic contributions. A free energy-surface area relationship served to calculate the nonpolar free energy term. The electr