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Electrostatic and structural properties of complexes involving plasmid DNA and cationic lipids commonly used for gene delivery

✍ Scribed by Nicolaas J Zuidam; Yechezkel Barenholz


Book ID
117048827
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
305 KB
Volume
1368
Category
Article
ISSN
0005-2736

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## Abstract A molecular‐diversity‐oriented approach for the preparation of well‐defined polycationic amphiphilic cyclodextrins (paCDs) as gene‐delivery systems is reported. The synthetic strategy takes advantage of the differential reactivity of primary versus secondary hydroxyl groups on the CD to