An ion trap mass spectrometer equipped with an electrospray source was used to examine the relative thermodynamic stabilities of various hemoglobins with respect to both tetramer dissociation and hemin dissociation. The results demonstrated that the stability of hemoglobin molecules can be different
Electrospray mass spectrometry in the clinical diagnosis of variant hemoglobins
β Scribed by C.H.L. Shackleton; A.M. Falick; B.N. Green; H.E. Witkowska
- Publisher
- Elsevier Science
- Year
- 1991
- Weight
- 694 KB
- Volume
- 562
- Category
- Article
- ISSN
- 0378-4347
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We here report the application of plasma desorption mass spectrometry in combination with reversed-phase high-performance liquid chromatography and automatic Edman sequencing for the characterization of hemoglobin variants. By use of plasma desorption mass spectrometry to obtain molecular weight inf
Six cephalosporins of pharmacological interest, cephalexin, cephuroxime, cephazolin, cephoperazone sodium salt, cephatrizin free acid and cephonicid disodium salt, were analysed by electrospray mass spectrometry. [ M Γ Na ]anions were produced in high yield in the case of cephalexin, cephuroxime, ce