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Electroporation-based DNA transfer enhances gene expression and immune responses to DNA vaccines in cattle

✍ Scribed by S. van Drunen Littel-van den Hurk; A. Luxembourg; B. Ellefsen; D. Wilson; A. Ubach; D. Hannaman; J.V. van den Hurk

Book ID
116960848
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
354 KB
Volume
26
Category
Article
ISSN
0264-410X

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Background Injection of DNA encoding exogenic proteins into muscle tissue combined with electroporation often results in a transient increase of the encoded protein concentration in the muscle and the blood. The reduction is normally due to an immune response against the exogenic protein but other f