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Electrophysiological examination of the effects of sustained flibanserin administration on serotonin receptors in rat brain

โœ Scribed by Lynne E Rueter; Pierre Blier

Book ID
110004100
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
550 KB
Volume
126
Category
Article
ISSN
0007-1188

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โœ Lynne E. Rueter; Claude De Montigny; Pierre Blier ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 251 KB ๐Ÿ‘ 1 views

Flibanserin (BIMT 17) has been described as a 5-HT 1A agonist with preferential affinity for postsynaptic 5-HT 1A receptors and as a 5-HT 2A antagonist. Indeed, using the forskolin-stimulated cAMP accumulation technique, flibanserin but not the 5-HT 1A agonists buspirone and 8-OH-DPAT had agonistic