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Electrophysiological actions of BRL 34915 in isolated guinea pig ventricular myocytes

✍ Scribed by Dr. John R. McCullough; Mary L. Conder; Louis H. Griffel


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
715 KB
Volume
19
Category
Article
ISSN
0272-4391

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## Abstract We investigated the potential involvement of peroxynitrite (ONOO^βˆ’^) in the modulation of calcium current (I~Ca~) in guinea pig ventricular myocytes with the whole‐cell patch clamp technique and with cyclic AMP (cAMP) measurements. Because of the short half‐life of ONOO^βˆ’^ at physiologi