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Electrophysiologic and radiocinematographic study of bile flow mechanism in human subjects

✍ Scribed by Watanabe, N. ;Ono, K. ;Narumi, H. ;Kumagai, T. ;Suzuki, K. ;Tsuchida, H.


Book ID
105615270
Publisher
Springer-Verlag
Year
1966
Tongue
English
Weight
154 KB
Volume
1
Category
Article
ISSN
0435-1339

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To test whether de nouo synthesis of cholesterol is a limiting factor for bile acid synthesis, we studied the acute effect of simvastatin, an inhibitor of HMGcoenzyme A reductase (the limiting step of cholesterol synthesis) on bile acid synthesis and biliary lipid secretion in subjects with interrup