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Electrophoretic Separation of Certain in vitro and in vivo Reactions of Rabbit Anti-Mouse Erythrocyte Serum

✍ Scribed by LEE, CHANG-LING; TAKAHASHI, TAMON; DAVIDSOHN, ISRAEL


Book ID
109610089
Publisher
Nature Publishing Group
Year
1960
Tongue
English
Weight
222 KB
Volume
187
Category
Article
ISSN
0028-0836

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We have studied the rate of transcription of t h e gene for dihydrofolate reductase (DHFR) in mouse 3T6 fibroblasts during serum-induced transitions between the resting (Go) and growing states. As a model system, we have used a methotrexate-resistant 3T6 cell line that overproduces DHFR and its mRNA