This paper reports an extension of the in-gel technique for releasing N-linked glycans from glycoproteins for analysis by matrix-assisted laser desorption/ ionization (MALDI) mass spectrometry reported by B. Ku ¨ster, S. F. Wheeler, A. P. Hunter, R. A. Dwek, and D. J. Harvey (1997, Anal. Biochem. 25
Electrophoretic analysis of the glycan microheterogeneity of orosomucoid in cancer and inflammation
✍ Scribed by John-Erik S. Hansen; SøRen P. Jensen; Bent Nørgaard-Pedersen; Thorkild C. Bøg-Hansen
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 445 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0173-0835
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Therapeutic monoclonal antibodies (mAbs), immunoglobulins, have been efficiently used in the treatment of many diseases, such as cancer, inflammatory and cardiovascular diseases, and organ transplantation. mAbs are glycoprotein molecules undergoing posttranslational modifications. Glyco
## Abstract The paraneoplastic syndrome of cachexia is considered a degenerative chronic inflammatory disease, being deeply related to the increase of pro‐inflammatory factors, especially tumour necrosis factor alpha (TNF‐__α__). It is known that the adipose tissue is affected by cachexia and contr
## Abstract When peripheral lymphocytes from patients with a history of cancer are incubated with encephalitogenic factor (EF), in 90% of cases the resulting products reduce the net surface negativity of guinea‐pig macrophages, used as detector cells, as revealed in the macrophage electrophoretic m
Oligosaccharides released from porcine thyroglobulin were first derivatised with 2-aminoacridone (2-AMAC) and analysed by capillary electrophoresis to determine the complexity of this glycan pool. The same glycan mixture was then subjected to either a sialidase digest or a sialidase and fucosidase d