Electrophilic substitution in benzo[b]thieno- and benzo[b]furo[2,3-c]pyridines. Use of the nuclear overhauser effect for determination of substitution position

Halogeno-substituted 2- and 3-methylbenz

Halogeno-substituted 2- and 3-methylbenzo[b]thiophenes: Use of 1H NMR spectral analysis and 1H{1H} nuclear Overhauser effect for locating the halogen substituent

✍ Ma. Rosa Cuberes; Marcial Moreno-Mañas; Francisco Sánchez-Ferrandom 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 582 KB

Thiiy-seven halogeno-substituted 2and 3-methyl-(or halogenomethyl)-benzo[b]thiophenes, including 17 new compounds, were prepared. The constitution of 14 of these was confirmed by full analysis (LAOCOON) of their 80MHz'HNMR spectra and by 'H{'H} NOE measurements. In this way a by-product from the pre