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Electronic structure and physico-chemical characteristics of imidazo[4,5-b]- and [4,5-c]pyridines and their protonated and deprotonated derivatives

โœ Scribed by A. G. Ignatenko; Yu. B. Vysotskii


Publisher
Springer US
Year
1994
Tongue
English
Weight
698 KB
Volume
30
Category
Article
ISSN
0009-3122

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Regioselective N-alkylation of imidazo[4
โœ Wael Zeinyeh; Julien Pilmรฉ; Sylvie Radix; Nadia Walchshofer ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 460 KB

S N 2 mechanism Tautomerism a b s t r a c t Regioselectivities were determined for N-alkylations of imidazo [4,5-b]pyridine-4-oxide and 2-methylimidazo [4,5-b]pyridine-4-oxide with benzyl bromide or benzyl iodide at RT using K 2 CO 3 in DMF as a base. Experimental attempts have shown that N-1/N-3 ra