Electronic Effects in the Lithium Borohydride Reduction of Styrene Oxides 1
β Scribed by Fuchs, Richard
- Book ID
- 118272380
- Publisher
- American Chemical Society
- Year
- 1956
- Tongue
- English
- Weight
- 245 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
In the course of an investigation of solvent effects on the relative reactivities of ketones with borohydridel, we have observed some unusual features of reductions in pyridine solvent which are relevant to recent discussions of the mechanism and stereochemistry of metal hydride reductions2,3,4,5 an
## Abstract The rates for the reduction of ketones with sodium borohydride are interpreted in terms of two parameters, both derived from forceβfield calculations; __i.e.__ the strain difference between alcohol and ketone (Ξ strain) and the steric hindrance towards approach of the hydride R. Models