✦ LIBER ✦

Electronic considerations in the mutagenesis of some 4,5-bridged chrysenes

✍ Scribed by Lee-Ruff, E. ;Raj, A. S. ;Kruk, H. ;Katz, M.

Book ID: 102186200
Publisher: Wiley (John Wiley & Sons)
Year: 1987
Weight: 408 KB
Volume: 9
Category: Article
ISSN: 0192-2521
DOI: 10.1002/em.2860090209

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✦ Synopsis

The mutagenic activity of four 4,5-bridged chrysene derivatives, benz(a)aceanthrylene, and 5methylchrysene was examined using histidine auxotrophic strains TA98 and TAlOO of Salmonella typhimurium. All compounds showed a positive mutagenic response with both TAlOO and TA98 in the presence of S-9. A correlation between the electronic character of the bridging group and mutagenic activity for the chrysene derivatives is proposed.

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