Electron Transfer through DNA: Site-Specific Modification of Duplex DNA with Ruthenium Donors and Acceptors

Investigation of the Pathways of Excess

Investigation of the Pathways of Excess Electron Transfer in DNA with Flavin-Donor and Oxetane-Acceptor Modified DNA Hairpins

✍ Sascha Breeger; Martin von Meltzer; Ulrich Hennecke; Thomas Carell 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 403 KB

## Abstract Oxetane is a potential intermediate that is enzymatically formed during the repair of (6–4) DNA lesions by special repair enzymes (6–4 DNA photolyases). These enzymes use a reduced and deprotonated flavin to cleave the oxetane by single electron donation. Herein we report synthesis of D