Electron microscopic and cytochemical studies of peroxidase-negative acute nonlymphoblastic leukemia
โ Scribed by M. Eguchi; Tetsuya Mikami; Hidemitsu Kurosawa; Kenichi Sugita; Toshiharu Furukawa; Saburo Tsunoda; Yasusada Miura
- Book ID
- 106239160
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 744 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0918-4287
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Peripheral-blood leukemic cells from 45 patients with peroxidase negative acute lymphoblastic leukemia (ALL), which did not express either myeloid or megakaryocyte-platelet-related cell surface antigens, were analyzed by using monoclonal antibodies capable of recognizing T-or B-cellassociated and/or
Ultrastructural cytochemical studies revealed peroxidase activity in five of 25 adult patients with apparent null lymphoblastic leukemia (ALL) in whom the peroxidase reaction studied with light microcopy was negative. None of these 5 patients responded to a chemotherapy regimen used for adult ALL. T