Electromagnetic stimulation on the bone growth using backscattered electron imaging

✍ Scribed by V Ottani; M Raspanti; D Martini; G Tretola; A Ruggeri Jr; M Franchi; G Giuliani Piccari; A Ruggeri

• Publisher: Elsevier Science
• Year: 2002
• Tongue: English
• Weight: 493 KB
• Volume: 33
• Category: Article
• ISSN: 0968-4328
• DOI: 10.1016/s0968-4328(01)00008-7

✦ Synopsis

The events at the hydroxyapatite implant material/tissue interface following electromagnetic stimulation were studied in the rabbit. Two kinds of hydroxyapatite were used: natural (NA) and synthetic (HA) both with a grain size of ,50 mm. Bone defects, arti®cially created in rabbit tibiae, were ®lled with the material examined. One group of animals was exposed immediately after surgery and every 12 h thereafter to 30-min treatments with electromagnetic ®elds (PEMFs). A second group was used as a control (untreated). Two and 4 weeks after implantation, animals were sacri®ced and bone samples processed for LM, TEM and SEM using a backscatter electron detector for the evaluation of bone growth. This study indicates that HA has more osteoconductivity than NA, and shows that PEMF-treatment results in a bene®t in accelerating bone formation at early time periods.