The mechanisms whereby electromagnetic (EM) fields stimulate changes in biosynthesis in cells are not known. It has generally been assumed that EM fields first interact with cell membranes, but this pathway may not be the only one. Interactions with membranes are well documented, but recent studies
Electromagnetic fields may act directly on DNA
β Scribed by Martin Blank; Reba Goodman
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 194 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0730-2312
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β¦ Synopsis
A wide variety of environmental stimuli induce the expression of stress response genes, including high temperatures, hypoxia, heavy metal ions, and amino acid analogs. Stress genes are also induced by low frequency magnetic fields. The cellular response to magnetic fields is activated by unusually weak stimuli, and involves pathways only partially associated with heat shock stress. Since magnetic fields interact with moving charges, as we have shown in enzymes, it is possible that magnetic fields stimulate the stress response by interacting directly with moving electrons in DNA. In this paper, we review several lines of evidence that support this hypothesis.
π SIMILAR VOLUMES
Blank and Goodman [(1997): Bioelectromagnetics 18:111 -115] suggest that weak extremely low frequency (ELF) electric and magnetic fields affect intracellular DNA directly. We show that such a conclusion is not in accord with physical principles.