𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Electrokinetics and stability of a cellulose acetate phthalate latex

✍ Scribed by P. Vera; V. Gallardo; J. Salcedo; M. A. Ruiz; A. V. Delgado


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
201 KB
Volume
65
Category
Article
ISSN
0021-8995

No coin nor oath required. For personal study only.

✦ Synopsis


An experimental investigation is described on the surface electric characterization of a commercially available latex, Aquateric, composed of cellulose acetate phthalate polymer particles, and used in enteric-controlled drug release. Since the surface charge of dispersed systems is an essential parameter governing most of their behavior, it is of fundamental importance to characterize how that quantity changes in the different environments in which the colloids could be used. The experimental method used in this work is electrophoresis; we report measurements of electrophoretic mobility of the latex as a function of pH and ionic concentration in the dispersion medium. It is shown that the zeta potential of the polymer particles is negative for the whole pH range studied and increases with pH as the dissociation of surface acetic acid groups proceeds. A plateau value is found for pH ΓΊ 5, corresponding to complete dissociation of available ionizable sites. The values of the electrophoretic mobility (m e ) and the zeta potential (z) of Aquateric are also analyzed as a function of the concentration of 1-1 (NaCl) and 2-1 (CaCl 2 ) concentration. The anomalous surface conductance (associated to the mobility of counterions adsorbed in the inner part of the electric double layer of the particles) manifests in a maximum in the Γ‰m e Γ‰-NaCl concentration plot for 10 03 M concentration. No such behavior is observed in the presence of CaCl 2 solutions, where only a decrease of the mobility with ionic strength is observed. The effect of AlCl 3 concentration on the mobility is also considered; it is found that at pH 2 aluminum ions adsorb on the particles and render them positively charged. When the pH of the suspensions is not maintained constant, the hydrolysis of aluminum gives rise to a less efficient control of the charge of the particles and no positive mobilities are observed. Electrophoretic mobility measurements as a function of pH at constant AlCl 3 concentration show an abrupt change of m e from negative to positive, interpreted as due to surface precipitation of Al(OH) 3 . When the pH is further increased, a second charge reversal is found, corresponding to the isoelectric point (pH of zero zeta potential) of Al(OH) 3 .


πŸ“œ SIMILAR VOLUMES


Quantitation of Cellulose Acetate Phthal
✍ A.Robert Neurath; Nathan Strick πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 52 KB

Cellulose acetate phthalate (CAP 2 ; Eastman Chemical Co., Kingsport, TN) is a cellulose derivative in which approximately one-half of the hydroxyl groups are acetylated and approximately one-fourth are esterified with one of the two acid groups of phthalic acid;

Covalent Binding of Proteins to Acetal-F
✍ J.M. Peula; R. Hidalgo-Alvarez; F.J. de las Nieves πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 English βš– 169 KB

In this work the interaction of an a-CRP IgG protein with science have made it possible to produce uniform latexes functionalized latexes that have acetal groups on their surfaces with desired size and surface characteristics. Thus, it is possihas been studied. Two acetal latexes with similar amount

Studies on dielectric relaxation and ac
✍ Vijayalakshmi Rao; P. V. Ashokan; J. V. Amar πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 338 KB πŸ‘ 2 views

## Abstract The dielectric constant, dielectric loss, and ac conductivity of polyblends of cellulose acetate hydrogen phthalate (CAP) and poly (vinyl pyrrolidone) (PVP) of different compositions were measured in the temperature range of 300–430 K and in the frequency range of 50 Hz–100 kHz. In the

Miscible blends of cellulose acetate hyd
✍ Vijayalakshmi Rao; P. V. Ashokan; M. H. Shridhar πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 216 KB πŸ‘ 2 views

Miscibility characteristics of cellulose acetate hydrogen phthalate (CAP) and poly(vinyl pyrollidone) (PVP) have been investigated by solution viscometric, ultrasonic, and differential scanning calorimetric (DSC) methods. From viscosity measurements, Krigbaum and Wall polymer-polymer interaction par