𝔖 Bobbio Scriptorium
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Electrochromatography in microchips packed with conventional reversed-phase silica particles

✍ Scribed by Attila Gaspar; Lilia Hernandez; Schetema Stevens; Frank A. Gomez

Book ID
102184959
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
272 KB
Volume
29
Category
Article
ISSN
0173-0835

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✦ Synopsis

Abstract

This paper shows the applicability of a disposable and inexpensive microfluidic chip for electrochromatographic separations. The chip, recently developed by us for chip‐based LC, was fabricated from PDMS incorporating conventional chromatographic RP silica particles (C18) without the use of frits. Three cephalosporin antibiotics were used to demonstrate the applicability of the chip‐based chromatographic packing for electrochromatographic determinations. The used sample injection method utilizes hydrodynamic pressure, thereby, reducing the propensity for sample bias during the injection.

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