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Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery

✍ Scribed by Mark J. Jaroszeski


Publisher
Humana Press
Year
2000
Tongue
English
Leaves
471
Series
Methods in Molecular Medicine
Edition
1
Category
Library

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✦ Synopsis


Leading experts comprehensively review all aspects of the delivery of therapeutic molecules to cells using electrical impulses-i.e., the extraordinarily promising new areas of electrogenetherapy, electrochemotherapy, and transdermal drug delivery. Their survey ranges from outlines of the basic physical principles that govern cell permeabilization by pulsed electric fields, to descriptions of the current state-of-the-art in instrumentation and electrodes, to summaries of preclinical and clinical trial results. The authors focus on drug, gene, and transdermal delivery techniques, providing detailed examples of drug delivery using electric fields from a variety of pulse generators and electrodes. Comprehensive and authoritative, Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery: Electrically Mediated Delivery of Molecules to Cells provides entrΓ© to an immensely practical set of in vivo electroporation techniques, including electrogenetherapy, electrochemotherapy, and transdermal drug delivery-techniques holding great promise for all those working toward better therapies for cancer, metabolic diseases, and vaccination.


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