Electrochemically Stimulated Release from Liposomes Embedded in a Polyelectrolyte Multilayer

✍ Scribed by Norma Graf; Francesco Albertini; Tristan Petit; Erik Reimhult; Janos Vörös; Tomaso Zambelli

• Book ID: 101415033
• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 395 KB
• Volume: 21
• Category: Article
• ISSN: 1616-301X
• DOI: 10.1002/adfm.201002283

✦ Synopsis

Abstract

Triggered release of an entrapped dye from vesicles embedded in a polyelectrolyte multilayer (PEM), as a consequence of the electrochemically induced local pH change in the vicinity of the electrode, is reported. The PEM was deposited on an indium tin oxide (ITO) electrode wherein lipid vesicles filled with a fluorescent dye were embedded. The use of vesicles with a strong negative charge and the polyelectrolyte species of the PEM matrix with a polycation as topmost layer enabled the generation of a stable layer of liposomes in the PEM.