## Abstract A sensitive amperometric glucose biosensor based on platinum nanoparticles (PtNPs) combined aligned carbon nanotubes (ACNTs) electrode was investigated. PtNPs which can enhance the electrocatalytic activity of the electrode for electrooxidating hydrogen peroxide by enzymatic reaction we
Electrochemical DNA Biosensors Based on Palladium Nanoparticles Combined with Carbon Nanotubes
✍ Scribed by Zhu Chang; Hao Fan; Kun Zhao; Miao Chen; Pingang He; Yuzhi Fang
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 200 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1040-0397
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✦ Synopsis
Abstract
Palladium nanoparticles, in combination with multi‐walled carbon nanotubes (MWCNTs), were used to fabricate a sensitivity‐enhanced electrochemical DNA biosensor. MWCNTs and palladium nanoparticles were dispersed in Nafion, which were used to modify a glassy carbon electrode (GCE). Oligonucleotides with amino groups at the 5′ end were covalently linked onto carboxylic groups of MWCNTs on the electrode. The hybridization events were monitored by differential pulse voltammetry (DPV) measurement using methylene blue (MB) as an indicator. Due to the ability of carbon nanotubes to promote electron‐transfer and the high catalytic activities of palladium nanoparticles for electrochemical reaction of MB, the sensitivity of presented electrochemical DNA biosensors was remarkably improved. The detection limit of the method for target DNA was 1.2×10^−13^ M.
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