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Electrochemical detection with microelectrodes in capillary flow systems

✍ Scribed by Frank-Michael Matysik; Antje Meister; Gerhard Werner

Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
650 KB
Volume
305
Category
Article
ISSN
0003-2670

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✦ Synopsis

A novel electrochemical cell for capillary electrophoresis with end-column amperometric detection is described. A platinum microdisk electrode (dpt = 25 pm> facing the capillary outlet served as sensing electrode. The problem of interference of the high voltage electrical field with the microelectrode circuit has been solved by the construction of a glass sleeve/Nafion joint for 100 pm i.d. capillaries. With 25 pm i.d. capillaries end-column detection could be performed without the use of an electrical-field decoupler arrangement. The analytical performance of the detector was characterized applying capillary zone electrophoresis and micellar electrokinetic capillary chromatography to separate various ferrocene derivatives. In addition, the same detector cell configuration has been used for amperometric detection in conjunction with capillary flow injection analysis.

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✍ P.C. Hauser; N.D. Renner; A.P.C. Hong πŸ“‚ Article πŸ“… 1994 πŸ› Elsevier Science 🌐 English βš– 516 KB

The use of potentiometric microelectrodes as detectors for anions in capillary electrophoresis is demonstrated. The detector electrode with a tip diameter of 3 pm is inserted into the end of a fused silica separation capillary with an internal diameter of 25 Frn. The separation and detection of Cl-