Electrochemical Detection of Uric Acid in Mixed and Clinical Samples: A Review

✍ Scribed by Dhana Lakshmi; Michael J. Whitcombe; Frank Davis; Piyush Sindhu Sharma; Bhim Bali Prasad

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 331 KB
• Volume: 23
• Category: Article
• ISSN: 1040-0397
• DOI: 10.1002/elan.201000525

✦ Synopsis

Abstract

The present review has sought to explore the technological advances that have been made in recent years towards the selective analysis of uric acid and critically evaluate how they could, in fact, be exploited as a basis for a multi analyte sensor incorporating uric acid detection. Numerous strategies have evolved in recent years but these have invariably focused on the manufacture and response characterization of discrete sensors. Various methods of obtaining selective detection such as use of uricase enzymes, nanoparticles, carbon nanotubes, polymers, conducting polymers and MIPs are also discussed along with the clinical relevance of UA determination.