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Electrochemical detection of individual DNA hybridization events

โœ Scribed by Alligrant, Timothy M. ;Nettleton, Elizabeth G. ;Crooks, Richard M.

Book ID
118062450
Publisher
Royal Society of Chemistry
Year
2013
Tongue
English
Weight
689 KB
Volume
13
Category
Article
ISSN
1473-0197

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## Abstract We report the new method for detection of DNA hybridization using enzymatic cleavage. The strategy is based on that S1 nuclease is able to specifically cleave only single strand DNA, but not double strand DNA. The capture probe DNA, thiolated single strand DNA labeled with electroactive