Electrochemical detection for trace analysis by capillary HPLC

✍ Scribed by Ruban, Vladimir F.

• Book ID: 102352630
• Publisher: John Wiley and Sons
• Year: 1993
• Tongue: English
• Weight: 298 KB
• Volume: 16
• Category: Article
• ISSN: 0935-6304
• DOI: 10.1002/jhrc.1240161108

✦ Synopsis

Abstract

An amperometric‐type electrochemical detector is proposed for use in capillary HPLC. Its cell (volume 60 nl) contains a cylindrical working electrode for detecting the presence of electroactive compounds. The noise level is 3–5 pA depending on the potential. The minimum detectable concentrations of the o‐, m‐, and p‐ isomers of nitrophenol (after separation of a 20 μl sample on a fused silica column) lies between 4 and 18 ng/l. The relative standard deviation of the height of the chromatographic peaks of phenols present at concentrations of 10 ppb does not exceed 0. 08 (n = 5).