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Electrochemical and enzymatic study of 2-chloro-2′-deoxyadenosine (antileukemic agent) and related compounds

✍ Scribed by Barbara Czochralska; Wiesław Kawczyński; Wojciech Bratkowski; Elżbieta Bojarska; Agnieszka Bzowska


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
645 KB
Volume
39
Category
Article
ISSN
1567-5394

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Reaction mechanism in the photochemistry
✍ Barbara Czochralska; Lars Lindqvist 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 590 KB

The reaction mechanism in the UV photochemistry of 2-chloro-2'-deoxyadenosine (Cladibrine) and 2-bromo-2'-deoxyadenosine in aqueous solution has been studied by laser photolysis at nanosecond time resolution. It is found that excitation at 266 nm wavelength produces heterolytic cleavage of the halog