Synthesis of [16,16,17α-2H3] estradiol a
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Ian J. Massey; Laszlo Tökés
📂
Article
📅
1981
🏛
John Wiley and Sons
🌐
French
⚖ 410 KB
## Abstract The title compounds, each of high isotopic purity, were synthesized as internal standards for the mass spectral quantitation of estradiol and estrone. The [^2^H~3~] estradiol **3** was obtained from estrone (**1**) by alkaline H/^2^H exchange of the C‐16 protons and LiAl^2^LH~4~ reducti