Protein-based analogues of conventional thermoplastic elastomers can be designed with enhanced properties as a consequence of the precise control of primary structure. Protein 1 undergoes a reversible sol±gel transition, which results in the formation of a well-defined elastomeric network above a lo
Elastin-Mimetic Synthetic Polypentapeptide Hydrogels
✍ Scribed by Jonghwi Lee
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 8 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract An elastin‐mimetic polypeptide, (EMM)~7~, with the amino‐acid sequence GRDPSS [VPGVG VPGKG VPGVG VPGVG VPGEG VPGIG]~7~ was used for chemical conjugation of various integrin ligands (RGD peptides) to prepare bioactive hydrogels. The chemical approach involved (1) chemical protection of l
## Abstract Synthetic elastin hydrogels are useful tissue engineering scaffolds because they present cell binding sequences and display physical performance similar to that of human elastic tissue. Small pores and a low porosity can limit cellular penetration into elastin scaffolds. To overcome thi