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Elastase-induced kupffer cell cytokine production is downregulated by gadolinium via NF-κB but not P38 MAP kinase

✍ Scribed by Yang, Jun; Jaffray, Colleen; Norman, James G.; Murr, Michel M.


Book ID
124144699
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
195 KB
Volume
120
Category
Article
ISSN
0016-5085

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## Abstract In response to inflammation stimuli, tumor necrosis factor‐α (TNF‐α) induces expression of cell adhesion molecules (CAMs) in endothelial cells (ECs). Studies have suggested that the nuclear factor‐κB (NF‐κB) and the p38 MAP kinase (p38) signaling pathways play central roles in this proc