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Elaboration of Simplified Vinca Alkaloids and Phomopsin Hybrids

✍ Scribed by Quoc Anh Ngo; Fanny Roussi; Sylviane Thoret; Françoise Guéritte

Book ID
111368794
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
869 KB
Volume
75
Category
Article
ISSN
1747-0277

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✍ J. R. F. Corvalan; W. Smith; V. A. Gore 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 French ⚖ 356 KB

The functional properties of a hybrid-hybrid monoclonal antibody (MAb) recognising both CEA and Vinca alkaloids have been explored in vivo in nude mice xenografted with MAWI, a human colorectal turnour. The hybrid-hybrid MAb localises specifically onto CEA-expressing tumour tissue and, furthermore,