Either a CD4+or CD8+T cell function is sufficient for clearance of infectious virus from trigeminal ganglia and establishment of herpes simplex virus type 1 latency in mice

Latency of herpes simplex virus type-1 i

Latency of herpes simplex virus type-1 in human geniculate and vestibular ganglia is associated with infiltration of CD8+ T cells

✍ Viktor Arbusow; Tobias Derfuss; Kathrin Held; Susanne Himmelein; Michael Strupp; 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 61 KB

## Abstract Herpes simplex virus type‐1 latency and CD8+ T‐cell occurrence were investigated in the trigeminal, geniculate, and vestibular ganglia from seven deceased humans. The HSV‐1 “latency‐associated transcript” was assessed by in situ hybridization and quantitative RT‐PCR. Infiltration of CD8