✦ LIBER ✦
Eine einfache Methode zur Herstellung von in Ring A ungesättigten 9, 11-Dehydro-16α-methyl-steroiden. Über Steroide, 162. Mitteilung
✍ Scribed by P. Wieland; K. Heusler; A. Wettstein
- Publisher
- John Wiley and Sons
- Year
- 1960
- Tongue
- German
- Weight
- 531 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
A study of the reactions involved in the preparation of 16α‐methyl‐17α‐hydroxy‐21‐acetoxy‐Δ^1;4;9,11^‐pregnatriene‐3, 20‐dione (V) from the corresponding 11α‐sulfonyloxy‐2,4‐dibromo‐allopregnane‐3,20‐diones led to a process in which all three substituents in 2‐, 4‐ and 11α‐positions are eliminated simultaneously. 2‐Halogen‐Δ^4;9,11^‐pregnadiene‐3,20‐diones were formed as by‐products which were reduced to the halogen‐free dienes.