𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Eine effiziente Synthese von 1-Triacontanol

✍ Scribed by Kirchner, Gerald ;Weidmann, Hans

Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
173 KB
Volume
1985
Category
Article
ISSN
0947-3440

No coin nor oath required. For personal study only.

✦ Synopsis

An Efficient Synthesis of 1‐Triacontanol

Reduction of 12‐dodecanolide (1), readily accesible from cyclododecanone, with diisobutylaluminium hydride afforded a 98:2 mixture of 12‐hydroxydodecanal (3) and 2‐oxa‐1‐cyclotridecanol (2). Its reaction with triphenyloctadecylphosphorane yielded 12‐triaconten‐1‐ol (4), the catalytic hydrogenation of which gave a total yield of 68% of 1‐triacontanol (5) starting from cyclododecanone.

📜 SIMILAR VOLUMES

Enzym-katalysierte Reaktionen, 13. Eine
Enzym-katalysierte Reaktionen, 13. Eine neue, effiziente Synthese von Fagomin
✍ Effenberger, Franz ;Null, Volker 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 233 KB

Enzyme‐Catalyzed Reactions, 13. — A New, Efficient Synthesis of Fagomine 2‐Deoxy‐L‐threo‐5‐hexulosonitrile (4) is obtained in excellent chemical yield by yeast transketolase (EC 2.2.1.1)‐catalyzed reaction of racemic 3‐hydroxy‐4‐oxobutyronitrile [(__R/S__)‐2] with lithium hydroxypyruvate (3). Catal