Eight New Diterpenoids from the Roots of Euphorbia nematocypha

✍ Scribed by Fei He; Jian-Xin Pu; Sheng-Xiong Huang; Wei-Lie Xiao; Li-Bin Yang; Xiao-Nian Li; Yong Zhao; Jian Ding; Cheng-Hui Xu; Han-Dong Sun

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: German
• Weight: 250 KB
• Volume: 91
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.200890230

✦ Synopsis

Abstract

From the dried roots of Euphorbia nematocypha, eight new diterpenoids, with ent‐atisane (i.e., 1–5) and isopimarane (i.e., 6–8) type skeletons, together with five known compounds, were isolated. The structures of these new compounds were elucidated by spectroscopic data. Compounds 1–8 were evaluated for their cytotoxicity against a small panel of human cancer cell lines.