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EGR-1 enhances tumor growth and modulates the effect of the Wilms' tumor 1 gene products on tumorigenicity

✍ Scribed by Scharnhorst, Volkher; Menke, Aswin L; Attema, Joline; Haneveld, Johan Klein; Riteco, Nicole; van Steenbrugge, Gert J; van der Eb, Alex J; Jochemsen, Aart G


Book ID
110062736
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
554 KB
Volume
19
Category
Article
ISSN
0950-9232

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## Abstract The Wilms' tumor 1 gene, __WT1__, encodes a zinc‐finger protein that is implicated in the development of Wilms' tumor. Mutant or aberrantly expressed WT1 isoforms have also been described in desmoplastic small round cell tumor, acute leukemias, mesothelioma, breast tumors and melanoma.