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EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans

✍ Scribed by Anne Smardon; Jill M. Spoerke; Steven C. Stacey; Marcia E. Klein; Nancy Mackin; Eleanor M. Maine


Book ID
114317499
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
717 KB
Volume
10
Category
Article
ISSN
0960-9822

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## Abstract Vasa and Belle are conserved DEAD box RNA helicases required for germ cell function. Homologs of this group of proteins in several species, including mammals, are able to complement a mutation in yeast (DED1) suggesting that their function is highly conserved. It has been proposed that