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Egg and sperm recognition systems during fertilization

✍ Scribed by Noritaka Hirohashi; Noriko Kamei; Hideo Kubo; Hitoshi Sawada; Midori Matsumoto; Motonori Hoshi


Book ID
118703587
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
214 KB
Volume
50
Category
Article
ISSN
0012-1592

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Mammalian eggs are surrounded by two egg coats: the cumulus oophorus and the zona pellucida, which is an extracellular matrix composed of sulfated glycoproteins. The first association of the spermatozoon with the zona pellucida occurs between the zona glycoprotein, ZP3 and sperm receptors, located a

Contribution of mouse egg zona pellucida
✍ Paul M. Wassarman πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 126 KB

## Abstract For sperm to fertilize eggs, they must first bind to the thick zona pellucida (ZP) that surrounds the plasma membrane of all unfertilized mammalian eggs. An extensive literature suggests that mouse sperm recognize and bind to a specific ZP glycoprotein called mZP3. However, the role of