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EGFR mutations detected on cytology samples by a centralized laboratory reliably predict response to gefitinib in non-small cell lung carcinoma patients

✍ Scribed by Malapelle, Umberto; Bellevicine, Claudio; De Luca, Caterina; Salatiello, Maria; De Stefano, Alfonso; Rocco, Danilo; de Rosa, Nicla; Vitiello, Fabiana; Russo, Stefania; Pepe, Francesco; Iaccarino, Antonino; Micheli, Pietro; Illiano, Alfonso; Carlomagno, Chiara; Piantedosi, Franco Vito; Troncone, Giancarlo

Book ID: 125928629
Publisher: Wiley (John Wiley & Sons)
Year: 2013
Tongue: English
Weight: 283 KB
Volume: 121
Category: Article
ISSN: 1934-662X
DOI: 10.1002/cncy.21322

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## Abstract The high frequency of epidermal growth factor receptor (__EGFR__) mutations in tyrosine kinase inhibitor‐responsive non‐small‐cell lung cancer (NSCLC) cases is now well established, highlighting the predictive value of activating __EGFR__ mutations in guiding the clinical use of __EGFR_