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EGFR, HER-2/neu, Cyclin D1, p21 and p53 in Correlation to Cell Proliferation and Steroid Hormone Receptor Status in Ductal Carcinomain situof the Breast

✍ Scribed by Annette Lebeau; Angela Unholzer; Gudrun Amann; Michaela Kronawitter; Ingo Bauerfeind; Andrea Sendelhofert; Anette Iff; Udo Löhrs


Book ID
111537717
Publisher
Springer US
Year
2003
Tongue
English
Weight
256 KB
Volume
79
Category
Article
ISSN
0167-6806

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TP53 alterations in relation to the cell
✍ Skomedal, Hanne; Kristensen, Gunnar B.; Nesland, Jahn M.; B�rresen-Dale, Anne-Li 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 283 KB 👁 2 views

In the present study, TP53 alterations have been analysed and compared with the expression of the proteins p21, cyclin D1, cdk4, RB, EGFR, and MDM2 in 53 cancers of the uterine corpus. TP53 gene mutations analysed by CDGE/DGGE and direct sequencing showed a TP53 gene mutation in 18 per cent of the c